THE IDEA
BEHIND
THE THINKER®
The human brain is the most complex object known to man kind, it is the most powerful in terms of processing information, and it is the core of our existence and what differentiate us from other species.
By Phd. Neuroscientist Alim H. Dokumaci
Dr. Alim Dokumaci
By Phd. Neuroscientist Alim H. Dokumaci
He is working to develop new products, and therapies. Interested in research and educational programs based on neuroscience. Nootropics, nervus vagus, Alzheimer’s disease and schizophrenia are some of his research area.
Overall insight to brain
The human brain contains roughly 90-100 billion neurons. The number of synaptic connections that neurons establish between themselves can sometimes reach up to 1000 for per neuron. Taking into account that human neuron cells cannot undergo the mitosis division
process, maintaining of brain’s normal physiological process is mainly depend
How does THE THINKER ® work ?
Our current model of the brain has basically trillions of neurons interconnected by axons and dendrites that emanate electric signals sending messages among neurotransmitters which play different roles in the inter-synaptic space modulating the electric signals.
Supplying the brain with the master formulation of the thinker may be great choice for our neurons.
Choline bitartrate
Supplementation of Choline has been shown to boost WRAML2 score (Wide Range Assessment of Memory and Learning, Second Edition)
Choline helps to improve cognitive performance by the way of being essential precursor molecule for acetylcholine synthesis. Choline bitartrate is uniquely qualified for the intensive task of brain cell communication as well as maintaining the synaptic connections of neurons and signaling functions of cell membranes. Also, choline supply either helps to support cognitive performance or assistance to relieve memory deficits.
Green tea
Standardized formulation (min. 20% caffeine and opt. catechins)
Since ancient ages, it has been believed that drinking green tea stimulate relaxation and moderation. Several experimental and human studies have shown that green tea and tea polyphenols (which include catechins and their derivatives), may help to provide brain activities as well as whole body.
To obtain its beneficial properties on our body, standardized green tea formulation can be taken daily.
Evidence about green tea consumption help to assist cognitive skills, positively.
Rhodiola rosea
R. rosea has been consuming to stimulate and maintain crucial neurotransmitters such as serotonin, norepinephrine, and dopamine. It can also support these neurotransmitters by the way of helping their transport across the brain from blood.
Due to its acetylcholine-protective and antioxidant properties , Rhodiola may help with mental progressing decline. There is also scientific data assert that R. rosea can help to improve cognitive skills which are declined by stress related hormones.
R. rosea also has known as its enhancing work capacity performance and reducing recovery time after exhaustive exercise/physical work.
More than 150 human attended scientific study has shown that R. rosea users feel better.
Ref: Phytomedicine : international journal of phytotherapy and phytopharmacology 10, 95-105
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Acetyl L-carnitin
Acetyl L-carnitine form is one of the carnitine formulation which help to provide brain functions and crosses blood-brain barrier more efficiently.
As reported in the majority of studies, an increase in maximal oxygen consumption and a lowering of the respiratory quotient indicate that carnitine has the potential to induce lipid metabolism. So, L-carnitine plays a crucial role in the production of energy by mitochondrial pathway.
Also L-carnitine supplementation can attenuate the deleterious effects of hypoxic training and speed up recovery from post exercise stress.
Preclinical study has shown that acetyl L-carnitine has better result about struggling to oxidative stress (increase when we under stress). Also higher levels of total carnitine detected in the same study.
Ref:Annals of the New York Academy of Sciences 1033, 117-131
L-Theanine
Alpha brain waves, related with alert relaxation and improved creativity, can be increased thanks to L-Theanine supplementation.
L-Theanine has been suggested by scientist to modulate the brain’s occipital and parietal regions that indicates relaxation without causing drowsiness.
Also it has taken into account that L-theanine gives opportunity to caffeine for showing brain-boosting activity without letting it increase blood pressure or induce anxiety.
This human study demonstrated that L-Theanine can decrease the score which was provoked by mental arithmetic stress task. Individuals who attended the study were grouped as control (no stress), placebo (under stress), L-Theanine (under stress with L-Theanine administration)
L-Tyrosine
L-Tyrosine is an amino acid that used as nutritional supplement. It has nootropic effect which help to augment brain function, improve the mood. Also L-Tyrosine help you to combat stress related cognitive declines such as depression.
Our brain vitally need L-Tyrosine, because it is a precursor for three fundamental neurotransmitters: dopamine, norepinephrine, and adrenaline. When excessive stress or working hard have reduced brain’s neurotransmitter stores, L-Tyrosine supplementation could help to reload them, allowing you to endure mentally sharp.
This human study has shown that L-Tyrosine can increase the level of alternate (elaboration) and remote uses task. Individuals who attended the study were grouped as placebo and L-Theanine administrated ones. Also supportive results in present study asserted that L-Tyrosine's benefical effects on cognitive skills.
Thiamine (Vitamin B1)
Thiamin is essential molecule for mitochondrial energy metabolism. Clinical studies have reported that an improvement detected with thiamine consumption such as being more clearheaded, composed and energetic. Although using of thiamine had no influence on memory, reaction times of individuals were detected faster following the supplementation of thiamine
Pantothenic acid (Vitamin B5)
Vitamin B5, also called pantothenic acid, is one of the most vital vitamin for human life. This vitamin is necessary for converting foods into energy, so neurons and other cells are starving to B5.
Due to people with a pantothenic acid deficiency are often experiencing other vitamin deficiencies, we should supply the lack of it.
Cyanocobalamine (Vitamin B12)
Vitamin-B12 is an essential molecule of normal physiological body and brain functioning. Lack of this vitamin can not be tolareted and cognitive defictions may be occur such as forgetfulness, amnesia and remembering problems. In addition to nervous system, vitamin-B12 also contributes to physological functioning of red blood cells, energy yielding metabolism
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All B vitamins work together to support maintaining brain process healthfully and optimally.
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There is several scientific evidence support that B1, B5 and B12 plays role in neuronal network processing
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Optimal B1, B5 and B12 intake can help us to decrease the modifiable risk factors for brain degeneration
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Cerebral energy metabolism, mood imbalance and cognitive enhancement are strongly related with our B vitamin levels
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B1+B5+B12 supplementation has been shown to help balance energy levels in a healthy range, that is also related with sharp overall mental performance
THE THINKER ® 's Algorithm
THE THINKER ® is entirely developed thinking in the brain; Helping in support your cognitive performance, which includes; memory, processing, decision making.
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